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After stratifying for age, sex and multimorbidity at baseline, our aim is to analyse time trends in incident multimorbidity and polypharmacy in the 15-year ...

Conditional DNA excision between two LoxP sites can be achieved in the mouse using Cre-ER(T), a fusion protein between a mutated ligand binding domain of ...

Mar 4, 2022 · Studies that reported health outcomes from Pb exposure without any link to genetic or epigenetic variation were excluded. Conference abstracts, ...

Objective. Given the challenges of patient‐provider communication in neurocritical care lacking robust decision‐making tools on prognostication, ...

Jun 1, 2023 · Microvesicles or medium EVs (200–1000 nm) are formed and secreted directly from the plasma membrane's outward budding. A new mechanism has been ...

Apr 21, 2022 · Purpose of Review. Environmental pollutants contribute to the pathogenesis of numerous diseases including chronic cardiovascular, ...

Mar 21, 2023 · Complex molecular mechanisms define our responses to environmental stimuli. Beyond the DNA sequence itself, epigenetic machinery ...